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Ethanol effects on hippocampal synaptic transmission and hippocampal function. Considering wide evidence, ethanol acutely alters the function of the hippocampus as measured in different cognitive tasks. A large amount of evidence shows alterations in structural plasticity inside hippocampal neurons, either dentate granule cells or pyramidal neurons. Glutamatergic transmission, especially that involving NMDAR function such as long-term potentiation, is also altered by ethanol.
