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Intrarenal haemodynamic function changes in mechanistic trials with SGLT2 inhibitors in T1D versus T2D. The figure illustrates potential mechanisms explaining the differences observed in two mechanistic trials with SGLT2 inhibitor in young adults (∼24 years of age) with T1D [ATIRMA study (NCT01392560)] and older adults (∼63 years of age) with T2D [RED (NCT02682563)].
