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. 2019 Dec 16;27(3):137–151. doi: 10.1530/ERC-19-0156

Table 1.

Genotypes of FOXE1 SNPs in thyroid cancer cell lines.

Cancer subtype Cell line Mutation SNPs genotype Other described mutations
rs1867277 rs965513 Poly Alanine
PTC BCPAP BRAF V600E G/G A/A 14/14 p53 D259Y/AKT1 copy gain
PTC K1 BRAF V600E A/A A/A 16/16 PI3KCA E542K
PTC KTC1 BRAF V600E G/A G/A 14/14
PTC NIM BRAF V600E G/G G/A 14/14
PTC TPC1 RET/PTC1 G/G G/G 14/14
FTC FTC-133 PTEN R130* A/A A/A 16/16 p53 R273H
FTC ML-1 G/G G/G 14/14 p53 frameshift
FTC TT206-C09 NRAS G/A G/G 14/14 p53 R273C
FTC WRO BRAF V600E A/A G/A 14/16
ATC 8505c BRAF V600E G/G G/G 14/14 p53 R248G
ATC C643 HRAS A/A G/G 14/14 p53 R248Q and K286E
ATC Cal62 KRAS G/G G/G 14/14 p53 A161D
ATC HTH7 NRAS A/A G/G 14/16 p53 G245S
ATC HTH83 HRAS G/A G/G 12/14
ATC KTC2 BRAF V600E G/G G/G 14/14
ATC OCUT2 BRAF V600E G/G G/G 14/14 PI3KCA H1047R
ATC SW1736 BRAF V600E A/A G/G 14/16 p53 Null
ATC T235 BRAF V600E G/G G/G 14/14
ATC T238 BRAF V600E A/A G/G 16/16 p53 S183*/PI3KCA E542K
NThyORI G/G G/A 14/14

The genotypes of the rs1867277, rs965513 SNPs and the length of the poly-alanine tract are shown in the central columns. The cancer subtype from which the cell lines originated, as well as the driver mutations, is also shown.