Figure 1.

The characteristics of CuS and cell biocompatibility in vitro and in vivo. A) Particle size distribution of CuS@BSA and TEM image; B) UV-vis absorption spectra of CuS@BSA in different doses and CuCl₂; C) Photothermal conversion of CuS@BSA in vitro under irradiation of 980 nm at P=2 W. D) The heat-cool loop of CuS@BSA in vitro under irradiation of 980 nm at P=2 W for 3 on and off cycles. E) IR thermal images of CuS@BSA dispersion in vitro under irradiation of 980 nm. F) IR thermal images of Matrigel or CuS@BSA with Matrigel dispersion in vivo under irradiation of 980 nm. The power transitions from 1 W to 0.8 W in CuS@BSA with Matrigel group to maintain 42 °C; G, H) MSCs survival after coculturing with CuS@BSA and CuCl₂ with or without laser irradiation by RTCA and MTT.