The evaluation of CuS@BSA under a laser in wound healing. A) Images of full-thickness skin defects in SD rat, blank Matrigel with laser, Matrigel + MSCs with laser, and Matrigel + CuS@BSA + MSCs with laser at 1, 7, and 14 days. B) Wound closure percentages calculated by formula mentioned in methods and materials of different groups at 7 and 12 days. C) Images of H&E and Masson's trichrome staining of the different groups at 7 and 12 days (Scale bar = 1 mm). The black arrows indicate the degree of healing. The magnified view in Masson's trichrome staining showed neonatal collagen (Scale bar=100 μm).