Table 1.

Progress of biomedical nanoparticles (NPs) in the clinical trials.^a

Study title / Diseases / Used nanoparticles	Progress / Locations
Pre-operative staging of pancreatic cancer using superparamagnetic iron oxide magnetic resonance imaging (SPIO MRI) / Pancreatic cancer / SPIONPs	Phase 4 (Completed)b / Massachusetts, US
Comparison of central venous catheters with silver nanoparticles versus conventional catheters central venous / Catheter related infections / Silver NPs (AgTive®)	Phase 4 (Completed) / ICU Rome, Italy
Clinical study on the harvesting lymph nodes with carbon nanoparticles for advanced gastric cancer / Advanced gastric cancer / Carbon NPs	Phase 3 (Unknown)c / Beijing, China
Multi-modality imaging (PCa) / prostate cancer, adenocarcinoma and neoplasm / [F-18]-DCFPyL injection (PET/MRI)	Phase 2 (Not recruiting)d / Ontario, Canada
Topical fluorescent nanoparticles conjugated somatostatin analog for suppression and bioimaging breast cancer / Breast cancer, skin cancer and diseases / CdS/ZnS core-shell type quantum dots coated with veldoreotide	Phase 1 (Recruiting)e / Qassim, Saudi Arabia

^a This information is acquired from https://clinicaltrials.gov.

^b Completed: The study has ended normally, and participants are no longer being examined or treated.

^c Unknown: The study has passed its completion date, and the status has not been last verified within the past 2 years.

^d Not recruiting: The study has not started recruiting participants.

^e Recruiting: The study is currently recruiting participants.