Figure 7.

Schematics of LIT mediated antitumor immune response for primary, secondary, and re-challenged and metastatic melanoma. (A) Schematic illustration of laser immunotherapy (LIT) for subcutaneous primary tumor and the timelines of the immune response in the tumor, serum and TDLNs. (B) Schematic of the treatment of secondary tumors by the combination of LIT and the anti-PD-1 antibody. (C) Schematic of the antitumor mechanism of LIT in the subcutaneous re-challenged tumors and lung metastasis.