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. 2020 Jan 1;10(4):1833–1848. doi: 10.7150/thno.39814

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The converse correlation between UCH-L1 and ERα. (A) The expressions of UCH-L1 and ERα in ERα (-) and ERα (+) breast cancer cells were measured by western blot. β-actin was used as a loading control. (B) Correlation between UCHL1 and ERα mRNA levels in GSE30682 (left) and GSE7390 (right) breast cancer samples. (C) A total of 169 clinical human breast carcinoma cases were subjected to immunohistochemical analyses with UCH-L1 antibody. The UCH-L1 expressions in representative tumor tissues including luminal A, luminal B, triple negative, and HER2 overexpression. (D) Immunohistochemical analyses of UCH-L1 expression in patients specimens.