Table 1.
Clinical and biochemical characteristics of participants (mean with s.d.).
Parameters | NC (n = 30) | NG (n = 30) | OC (n = 11) | OG (n = 30) |
---|---|---|---|---|
Age (years) | 22.1 ± 1.64 | 25.1 ± 4.27 | 25.3 ± 1.61 | 26.9 ± 4.86 |
Hirsutism score | 0.53 ± 2.06 | 7.73 ± 2.65b | 0.64 ± 0.67 | 6.13 ± 3.22d |
Acne score | 0.47 ± 0.52 | 1.43 ± 1.47b | 0.45 ± 0.52 | 0.55 ± 0.95 |
LH (IU/L) | 6.63 ± 1.08 | 11.3 ± 1.15a | 6.23 ± 0.75 | 5.80 ± 1.61 |
FSH (IU/L) | 7.07 ± 0.67 | 6.62 ± 1.59 | 7.76 ± 1.76 | 5.97 ± 1.17c |
LH/FSH | 0.54 ± 0.20 | 1.72 ± 0.50b | 0.83 ± 0.15 | 0.87 ± 0.49c |
Testosterone (μg/L) | 0.48 ± 0.03 | 0.77 ± 0.06b | 0.52 ± 0.10 | 0.76 ± 0.16c |
E2 (pg/mL) | 40.6 ± 2.13 | 50.8 ± 5.68b | 39.4 ± 2.36 | 43.2 ± 9.54 |
DHEA (μg/dL) | 200 ± 66.2 | 276 ± 105b | 232 ± 37.1 | 290 ± 114.5 |
FBG (µIU/mL) | – | 2.38 ± 3.10 | 6.32 ± 7.14 | |
IAUC | – | 0.023 ± 0.017 | 0.012 ± 0.03 | |
HOMA-IR | – | 2.36 ± 3.20 | 6.35 ± 0.17 | |
ISI | – | 0.029 ± 0.01 | 0.014 ± 0.02 | |
Insulin_0min (µIU/mL) | – | 11.9 ± 2.10 | 21.2 ± 4.03 | |
Insulin_30min (µIU/mL) | – | 89.2 ± 2.93 | 104 ± 1.71 | |
Insulin_60min (µIU/mL) | – | 85.3 ± 4.31 | 134 ± 3.17 | |
Insulin_120min (µIU/mL) | – | 45.5 ± 2.57 | 74.6 ± 2.39 | |
Insulin_180min (µIU/mL) | – | 24.9 ± 2.2 | 45.2 ± 2.55 |
aP < 0.05 compared with NC; bP < 0.01 compared with NC; cP < 0.05 compared with OC; dP < 0.01 compared with OC.
DHEA, dehydroepiandrosterone; E2, estradiol; FBG, fasting blood glucose; FSH, follicle-stimulating hormone; HOMA-IR, homeostatic model assessment for insulin resistance; IAUC, insulin area under the curve; Insulin_Xmin, serum insulin levels after a 75 g glucose load at X minutes; ISI, insulin sensitive index; LH, luteinizing hormone; NC, non-obese control group; NG, non-obese group with PCOS; OC, obese control group; OG, obese group with PCOS.