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. 2020 Jan 24;9:1478. doi: 10.3389/fonc.2019.01478

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Copyright © 2020 Zhang, Wang, Zhang, Chen, He and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The receiver operating characteristic curves and diagnostic performances of the model for the diagnosis of liver cirrhosis complicated with hepatocellular carcinoma. (A) Training set; (B) validation set; (C) all patient set; (D) the set of patients with AFP < 400 μg/L; (E) the set of patients with AFP < 200 μg/L; (F) the set of patients with AFP < 20 μg/L. AUROC, area under the receiver operating characteristic curve; CI, confidence interval; LCC, liver cirrhosis complicated with hepatocellular carcinoma; LC, liver cirrhosis; AFP, alpha-fetoprotein; SEN, sensitivity; SPE, specificity; ACC, accuracy; PPV, positive predictive value; NPV, negative predictive value; PLR, positive likelihood ratio; NLR, negative likelihood ratio.