Table 4:
Comparative analysis of changes in oxidative stress parameters in groups of COPD-only patients and patients with combined COPD and hypertension within one genotype of the AGT gene.
Parameters | 8-isoprostane | Н2О2 | О2•- |
---|---|---|---|
M/M genotype | |||
Kruskal-Wallis test and its respective test of significance | Н=13.25; р=0.001* |
Н=16.01; р<0.001* |
Н=16.04; р<0.001* |
Mann–Whitney U test in pairwise comparison of groups | р1-2=0.074 р2-3=0.003* р1-3=0.004* |
р1-2=0.003* р2-3=0.003* р1-3=0.004* |
р1-2=0.003* р2-3=0.003* р1-3=0.004* |
M/T genotype | |||
Kruskal-Wallis test and its respective test of significance | Н=32.27; р<0.001* |
Н=37.68; р<0.001* |
Н=37.86; р<0.001* |
Mann–Whitney U test in pairwise comparison of groups | р1-2=0.001* р2-3<0.001* р1-3<0.001* |
р1-2<0.001* р2-3<0.001* р1-3<0.001* |
р1-2<0.001* р2-3<0.001* р1-3<0.001* |
T/T genotype | |||
Kruskal-Wallis test and its respective test of significance | Н=2.58; р=0.276 |
Н=4.42; р=0.111 |
Н=4.45; р=0.108 |
Note: H = Kruskal-Wallis test; p = the significance test of the latter.