Table 2.

Cardiac characteristics of Glu54Gln-mutated ATTR

Cardiac characteristics	Glu54Gln ATTR (7 patients)
Age, years	45.9
Sex, % male	28.5%
NT-proBNP (pg/ml), mean [range]	2815.6 [34.5–7140]
IVS thickness, mm, mean [range]	16 [13–21]
PW thickness, mm, mean [range]	15 [12–17]
RV free wall thickness, mm, mean [range]	7 [5–8]
S′, cm/s, mean [range]	5.4 [4–7]
E/A, mean [range]	2.3 [0.9–4.2]
E/E’, mean [range]	19 [10–26]
TAPSE, mean [range]	19 [13–26]
GLS, %, mean [range]	−13 [−7.7, −18.5]
Atrial fibrillation, n, %	2 (15%)
AV block, n, %	5 (38%)
RBBB, n, %	4 (31%)
LBBB, n, %	1 (8%)
LVEF %, mean [range]	49 [30–60]
Pericardial effusion, n, %	2 (15%)

A late phase mitral wave velocity, AV block atrioventricular block, E early mitral wave velocity, E’ early diastolic mitral annulus velocity, GLS global longitudinal strain, IVS interventricular septum, LBBB left bundle branch block, LVEF left ventricular ejection fraction, NT-proBNP N-terminal-pro hormone B-type natriuretic peptide, PW posterior wall, RV thickness right ventricular thickness, RBBB right bundle branch block, S′ mitral annulus systolic myocardial velocity, TAPSE Tricuspid annular plane systolic excursion