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. 2020 Jan 30;15:34. doi: 10.1186/s13023-020-1309-9

Table 3.

Neurological characteristics of Glu54Gln-mutated ATTR

Neurological characteristics at diagnosis for symptomatic patients Glu54Gln ATTR
NIS-LL, mean, range (N = 8) 13.4 [4–26]
mBMI, (g/l) x (kg/m2), mean, range (N = 8) 1084 [611–1444]
PND scale (8 patients) Grade I, n (%) 5 (63%)
Grade II, n (%) 3 (37%)
Polyneuropathy, n (%) (N = 13) 12 (92%)
Carpal tunnel syndrome, n (%) (N = 13) 7 (53%)
Orthostatic hypotension, n (%) (N = 13) 9 (69%)
Diarrhea, n (%) (N = 13) 4 (31%)
Constipation, n (%) (N = 13) 5 (38%)
Weight loss, n (%) (N = 13) 8 (62%)

mBMI modified body mass index, NIS-LL neuropathy impairment score of lower limbs, PND polyneuropathy disability score