Table 2.
Distribution of VDR genotypes between OLP and control group
| Genotype | OLP | Control | OR (95% CI) | P-value |
|---|---|---|---|---|
| rs731236 | ||||
| CC | 154 (87.01) | 180 (86.96) | 1.00 | – |
| CT | 21 (11.86) | 24 (11.59) | 0.99 (0.51–1.91) | 0.979 |
| TT | 2 (1.13) | 3 (1.45) | 0.93 (0.15–6.06) | 0.946 |
| Dominant | 0.99 (0.52–1.85) | 0.965 | ||
| Recessive | 0.94 (0.15–6.05) | 0.947 | ||
| Additive | 0.98 (0.57–1.71) | 0.954 | ||
| rs739837 | ||||
| CC | 98 (55.37) | 112 (54.11) | 1.00 | – |
| CA | 61 (34.46) | 82 (39.61) | 0.73 (0.45–1.20) | 0.218 |
| AA | 18 (10.17) | 13 (6.28) | 1.36 (0.60–3.09) | 0.468 |
| Dominant | 0.82 (0.51–1.31) | 0.404 | ||
| Recessive | 1.60 (0.73–3.50) | 0.242 | ||
| Additive | 0.98 (0.69–1.41) | 0.927 | ||
| rs757343 | ||||
| AA | 113 (63.84) | 128 (61.84) | 1.00 | – |
| AG | 53 (29.94) | 73 (35.27) | 0.70 (0.43–1.15) | 0.163 |
| GG | 11 (6.21) | 6 (2.90) | 2.06 (0.70–6.13) | 0.180 |
| Dominant | 0.81(0.50–1.29) | 0.375 | ||
| Recessive | 2.36 (0.81–6.89) | 0.117 | ||
| Additive | 0.97 (0.66–1.44) | 0.893 | ||
| rs2107301 | ||||
| CC | 83 (46.89) | 96 (46.38) | 1.00 | – |
| CT | 79 (44.63) | 93 (44.93) | 1.03 (0.67–1.60) | 0.883 |
| TT | 15 (8.47) | 18 (8.70) | 1.19 (0.54–2.58) | 0.668 |
| Dominant | 1.06 (0.69–1.61) | 0.800 | ||
| Recessive | 1.17 (0.55–2.45) | 0.686 | ||
| Additive | 1.07 (0.77–1.48) | 0.706 | ||
| rs2239185 | ||||
| CC | 90 (50.85) | 111 (53.62) | 1.00 | – |
| CT | 62 (35.03) | 83 (40.10) | 0.78 (0.47–1.27) | 0.315 |
| TT | 25 (14.12) | 13 (6.28) | 2.39 (1.10–5.18) | 0.027 |
| Dominant | 1.00 (0.63–1.59) | 0.995 | ||
| Recessive | 2.68 (1.28–5.62) | 0.009 | ||
| Additive | 1.24 (0.88–1.74) | 0.206 | ||
| rs7975232 | ||||
| AA | 81 (45.76) | 118 (57.00) | 1.00 | – |
| AC | 70 (39.55) | 74 (35.75) | 1.36 (0.83–2.23) | 0.225 |
| CC | 26 (14.69) | 15 (7.25) | 2.65 (1.24–5.66) | 0.012 |
| Dominant | 1.57 (0.97–2.50) | 0.061 | ||
| Recessive | 2.25 (1.10–4.58) | 0.026 | ||
| Additive | 1.54 (1.09–2.18) | 0.014 | ||
| rs11574129 | ||||
| CC | 119 (67.23) | 146 (70.53) | 1.00 | – |
| CT | 50 (28.25) | 57 (27.54) | 0.97 (0.59–1.61) | 0.921 |
| TT | 8 (4.52) | 4 (1.93) | 2.49 (0.70–8.84) | 0.159 |
| Dominant | 1.08 (0.67–1.75) | 0.740 | ||
| Recessive | 2.50 (0.71–8.84) | 0.154 | ||
| Additive | 1.17 (0.78–1.76) | 0.439 | ||
| rs11568820 | ||||
| AA | 61 (34.46) | 74 (35.75) | 1.00 | – |
| AG | 81 (45.76) | 96 (46.38) | 1.10 (0.69–1.76) | 0.695 |
| GG | 35 (19.77) | 37 (17.87) | 1.26 (0.69–2.28) | 0.454 |
| Dominant | 1.14 (0.74–1.78) | 0.551 | ||
| Recessive | 1.19 (0.70–2.03) | 0.520 | ||
| Additive | 1.12 (0.83–1.50) | 0.455 | ||
Logistic regression analyses adjusted for age, gender, alcohol, oral hygiene
Abbreviation:VDR vitamin D receptor, OLP oral lichen planus, OR odds ratio, CI confident interval