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. 2020 Jan 31;17:43. doi: 10.1186/s12974-020-1718-7

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© The Author(s). 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — SR9009 application attenuated microglial activation in the pilocarpine-induced SE model. a Iba1 immunofluorescence staining in the CA1 and CA3 regions of the hippocampus in the four groups. b, c The number of microglia was drastically decreased in SR9009-treated pilocarpine mice compared with vehicle-treated pilocarpine mice. d Western blotting analysis demonstrated that SR9009 significantly reduced the protein level of Iba1 in the hippocampus after SE. n = 3 for each group. The data presented as the mean ± SD. NS, not significant, ^†p < 0.001. Scale bar = 50 μm