Table 2.
Expression of p16INK4A in CINs and ISCCs
Tissues | Degree of immunoreactivity(%) | |||
---|---|---|---|---|
– | 1+ | 2+ | 3+ | |
Normala | 36/36 (100.0) | 0/36 (0.0) | 0/36 (0.0) | 0/36 (0.0) |
CIN Ib | 1/50 (2.0) | 31/50 (62.0) | 15/50 (30.0) | 3/50 (6.0) |
CIN IIc | 1/52 (1.9) | 5/52 (9.6) | 27/52 (51.9) | 19/52 (36.5) |
CIN IIId | 0/44 (0) | 6/44 (13.6) | 25/44 (56.8) | 13/44 (29.5) |
ISCCse | 0/61 (0) | 16/61 (26.2) | 14/61 (23.0) | 31/61 (50.8) |
CIN cervical intraepithelial neoplasia, ISCCs invasive squamous cell carcinomas
a-bP < 0.005, a-cP < 0.005, a-dP < 0.005, a-eP < 0.005, b-cP < 0.005, b-dP < 0.005,
b-eP < 0.005, c-dP > 0.05, c-eP > 0.05, d-eP > 0.05;