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. 2020 Jan 30;15:6. doi: 10.1186/s13027-020-0272-3

Table 2.

Expression of p16INK4A in CINs and ISCCs

Tissues Degree of immunoreactivity(%)
1+ 2+ 3+
Normala 36/36 (100.0) 0/36 (0.0) 0/36 (0.0) 0/36 (0.0)
CIN Ib 1/50 (2.0) 31/50 (62.0) 15/50 (30.0) 3/50 (6.0)
CIN IIc 1/52 (1.9) 5/52 (9.6) 27/52 (51.9) 19/52 (36.5)
CIN IIId 0/44 (0) 6/44 (13.6) 25/44 (56.8) 13/44 (29.5)
ISCCse 0/61 (0) 16/61 (26.2) 14/61 (23.0) 31/61 (50.8)

CIN cervical intraepithelial neoplasia, ISCCs invasive squamous cell carcinomas

a-bP < 0.005, a-cP < 0.005, a-dP < 0.005, a-eP < 0.005, b-cP < 0.005, b-dP < 0.005,

b-eP < 0.005, c-dP > 0.05, c-eP > 0.05, d-eP > 0.05;