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. 2020 Jan 30;21:37. doi: 10.1186/s12931-020-1292-7

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© The Author(s). 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Correlations between FEV₁ percent variation (Δ) and Δ Nrf2/ARE gene expression in COPD patients. a Correlation between FEV₁ and Nrf2 mRNA expression in PBMCs. b Correlation between FEV₁ and HO-1 mRNA expression in PBMCs. c Correlation between FEV₁ and GCLC mRNA expression in PBMCs. Abbreviations: GCLC, glutamate-cysteine ligase catalytic; HO-1, heme oxygenase-1; mRNA, messenger RNA; Nrf2, nuclear factor-E2-related factor 2; PBMCs, peripheral blood mononuclear cells