Table 2.
Hierarchical stepwise linear regression considering FEV1% variation as dependent variable and Nrf2, HO-1 and GCLC mRNA, plasma GSH, plasma 8-iso % variation and baseline smoking history (pack-year) as independent variables in COPD group (n.33)
| Independent variable | Standardized Beta coefficients | P value | R2 | Predicted R2 |
|---|---|---|---|---|
| FEV1% variation | ||||
| Nr2 mRNA (% variation) | 0.405 | 0.001 | ||
| HO-1 mRNA (% variation) | 0.364 | 0.006 | ||
| GCLC mRNA (% variation) | 0.322 | 0.015 | ||
| plasma 8-iso (% variation) | 0.096 | 0.315 | ||
| plasma GSH (% variation) | 0.074 | 0.403 | ||
| pack-year | 0.059 | 0.477 | ||
| 0.895 | 0.881 | |||