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. 2020 Jan 30;19:12. doi: 10.1186/s12933-020-0988-9

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Associations of CHD PRS with CHD and clinical risk factors among individuals of European ancestry with type 2 diabetes. Associations were tested using logistic regression model adjusted for age and sex. Results presented are based on diabetic participants of British ancestry in the UK Biobank (N = 21,102) or participants of European ancestry in the MCCD cohort (N = 310). HD heart disease, OR odds ratio, CI confidence interval. ORs are presented on a logarithmic scale as squares with corresponding CIs indicated by solid lines. Arrows indicate CIs beyond the illustrated range