Table 1.
Clinical characteristics in the population of British ancestry in the UK Biobank with type 2 diabetes
| Participants (n = 21,102) | Participants with information (%) | |
|---|---|---|
| CHD (%) | 1898 (9.0) | 21,102 (100) |
| Mean CHD PRSa (SD) | 16.49 (0.08) | 21,102 (100) |
| Men (%) | 13,010 (61.7) | 21,102 (100) |
| Median age (IQR) | 62 (56–66) | 21,102 (100) |
| Hypertension (%) | 14,899 (70.6) | 21,102 (100) |
| Systolic hypertension (%) | 10,837 (54.6) | 19,866 (94.1) |
| Diastolic hypertension (%) | 3551 (17.9) | 19,866 (94.1) |
| Antihypertensive drug usage (%) | 8697 (41.2) | 21,102 (100) |
| Hyperlipidemia (%) | 19,964 (94.6) | 21,102 (100) |
| High LDL (%) | 18,280 (91.2) | 20,035 (94.9) |
| Hypertriglyceridemia (%) | 418 (2.0) | 20,055 (95.0) |
| Lipid-lowering drug usage (%) | 10,077 (47.8) | 21,102 (100) |
| Poor glycemic control (%) | 3406 (16.9) | 20,171 (95.6) |
| Median BMI (IQR) | 30.80 (27.50–34.80) | 20,347 (96.4) |
| Smoking history (%) | 14,039 (66.9) | 20,971 (99.4) |
| Family history of heart disease (%) | 10,560 (50.0) | 21,102 (100) |
a Non-standardized PRS is reported in this table to allow comparison with other cohorts. All subsequent analyses adopted standardized PRS