Table 3.
Breed | Chr | Start | End | Number of suggestive and significant SNPs | Most significant SNP | P-value | Allele frequency of + allele | Candidate genes within this QTL | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
AA | CH | HE | LM | SI | ||||||||
AA | 1 | 146687440 | 147685998 | 7 | 147187440b | 9.55 × 10−7 | 0.988 | 0.712 | 0.073 | 0.179 | 0.631 | TRAPPC10, COL18A1, SLC19A1, PCBP3e, COL6A1, COL6A2 |
4 | 69229353 | 70999401 | 38 | 70373241a | 4.19 × 10−7 | 0.991 | 0.015 | 0.990 | 0.014 | 0.900 | HOXA1, HOXA2, HOXA3, HOXA4, HOXA5, HOXA6, HOXA7, HOXA9, HOXA10, HOXA11, HOXA13 | |
24 | 36998437 | 38030390 | 4 | 37530390bd | 2.24 × 10−7 | 0.977 | 0.000 | 0.014 | 0.036 | 0.983 | NDC80, EMILIN2e, MYOM1, MYL12A, MYL12B | |
25 | 35042698 | 36122096 | 6 | 35542698a | 3.50 × 10−7 | 0.998 | 0.000 | 0.000 | 0.000 | 0.002 | POLR2J, MYL10, ALKBH4, COL26A1 | |
29 | 23787949 | 24826548 | 7 | 24290699a | 1.82 × 10−7 | 0.048 | 0.043 | 0.937 | 0.939 | 0.919 | SLC6A5, PRMT3 | |
CH | 2 | 7850 | 10711228 | 5075 | 6808074a | 9.07 × 10−49 | 0.000 | 0.079 | 0.000 | 0.028 | 0.005 | WDR75f, ASNSD1f, NAB1f, MFSD6f, MSTNf, PMS1f, ORMDLe COL3A1, COL5A2f, ANKARf, SLC40A1f |
14 | 33353270 | 34360874 | 4 | 33855595a | 2.20 × 10−7 | 0.013 | 0.026 | 0.054 | 0.054 | 0.018 | ARFGEF1, CPA6, PREX2 | |
14 | 67849241 | 68850085 | 4 | 6834924a | 2.69 × 10−6 | 0.000 | 0.062 | 0.000 | 0.000 | 0.000 | STK3, KCNS2, POP1, RPL30, MATN2 | |
16 | 60443313 | 62320499 | 4 | 60943313a | 6.72 × 10−6 | 0.904 | 0.230 | 0.063 | 0.853 | 0.821 | RASAL2, ANGPTL1, TOR3A, ABL2, SOAT1 | |
29 | 21313583 | 22460213 | 38 | 21917306a | 3.58 × 10−6 | 0.000 | 0.989 | 0.000 | 0.978 | 0.000 | GAS2, FANCF | |
HE | 4 | 3924012 | 5000928 | 3 | 4424012a | 4.05 × 10−7 | 0.755 | 0.032 | 0.082 | 0.000 | 0.939 | ENSBTAG00000023806 |
7 | 72100887 | 73679002 | 67 | 72608186b | 9.09 × 10−7 | 0.000 | 0.998 | 0.046 | 0.000 | 0.995 | EBF1e, ADRA1B | |
13 | 6038290 | 8341939 | 9 | 7003978a | 1.84 × 10−7 | 0.000 | 0.000 | 0.002 | 0.004 | 0.000 | ESF1, NDUFAF5, FLRT3 | |
14 | 57257740 | 58269158 | 3 | 57757740a | 7.98 × 10−7 | 0.262 | 0.122 | 0.758 | 0.104 | 0.000 | TRHR | |
25 | 37995664 | 39005834 | 3 | 38505834c | 2.68 × 10−7 | 0.160 | 0.928 | 0.097 | 0.056 | 0.071 | LMTK2, PMS2, EIF2AK1, USP42 | |
LM | 2 | 313343 | 3758925 | 102 | 3226165a | 5.94 × 10−10 | 0.907 | 0.032 | 0.997 | 0.066 | 0.057 | NIPA1, NIPA2e, ARHGEF4 |
2 | 4973733 | 11101064 | 2441 | 6747317a | 2.20 × 10−28 | 0.802 | 0.409 | 0.617 | 0.074 | 0.490 | WDR75, ASNSD1f, NAB1f, MFSD6e, MSTNf, PMS1f, ORMDL1e, COL3A1e, COL5A2f, ANKARf, SLC40A1f | |
2 | 11556240 | 12618550 | 36 | 12116324a | 1.36 × 10−8 | 0.308 | 0.402 | 0.231 | 0.195 | 0.556 | ZNF804A | |
2 | 13935604 | 14957932 | 55 | 14447892bc | 1.67 × 10−6 | 0.433 | 0.562 | 0.374 | 0.394 | 0.524 | PDE1Ae, PPP1R1C, NEUROD1 | |
4 | 23124509 | 24137261 | 59 | 23630609b | 2.52 × 10−7 | 0.096 | 0.027 | 0.996 | 0.994 | 0.010 | AGMOe, MEOX2 | |
SI | 1 | 22558133 | 23622641 | 49 | 23117106a | 5.21 × 10−6 | 0.949 | 0.043 | 0.866 | 0.060 | 0.870 | ENSBTAG00000046369 |
14 | 79492849 | 80610485 | 17 | 80090294b | 2.33 × 10−7 | 0.104 | 0.052 | 0.980 | 0.886 | 0.072 | E2F5 | |
17 | 21615210 | 22651417 | 8 | 22115210a | 1.47 × 10−6 | 0.474 | 0.619 | 0.639 | 0.359 | 0.297 | ENSBTAG00000044703 | |
21 | 17057917 | 18336523 | 18 | 17836523a | 5.30 × 10−8 | 0.003 | 0.010 | 0.000 | 0.000 | 0.997 | ENSBTAG00000045960 | |
22 | 33706576 | 34737653 | 10 | 34236342b | 2.08 × 10−6 | 0.000 | 0.995 | 0.000 | 0.987 | 0.002 | SUCLG2e, KBTBD8 |
SNP classification: aintergenic, bintron, cupstream gene variant, ddownstream gene variant
Significance of SNPs within genes: egene contains at least one suggestive SNP, fgene contains at least one significant SNP