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Search of integrin inhibitors to inhibit the cross-talk between TGF-β and periostin. (A) Structures of integrin inhibitor–related molecules. The different portions from CP4715 are depicted in red. (B and C) Effects of each compound on the adhesion of periostin or vitronectin to integrin αVβ3 (B) or on the luciferase activity in the reporter cells harboring the SBE-conjugated luciferase gene (C). Half-maximal inhibitory concentration values of each compound are depicted. **P < 0.01.
