Figure-2: BACE1 and p75 expression are enhanced following CCI in the mouse brain.
a) Schematic diagram represents CCI conducted on the left somatosensory cortex of mice at P90. b) A coronal section of mice brain stained with DAPI represents the region of implemented CCI. c) Immunostaining assay demonstrates BACE1 (green) and p75 (red) in both CCI and sham groups 72 hours after CCI. “Merge” is the combination of DAPI (blue), BACE1, and p75. White arrows indicate the cells, expressing both BACE1, and p75 within 300 μm from the injury site. The white dashes on the green channel indicate CCI region. n=6 mice, scale bar: 200 μm.