. 2020 Jan 28;8:e8050. doi: 10.7717/peerj.8050

Table 2. Univariate and multivariate Cox regression analysis of overall survival in GC patients.

Variables	Univariate analysis			Multivariate analysis
	P value	HR	95% CI	P value	HR	95% CI
Age (≤60 vs. >60)	0.007	1.023	(1.006–1.040)	<0.000	1.037	(1.019–1.055)
Gender (Female vs. Male)	0.144	0.767	(0.537–1.095)	0.42	0.861	(0.598–1.239)
Tumor grade (G1 vs. G2 vs. G3)	0.011	1.466	(1.090–1.971)	<0.000	1.763	(1.294–2.402)
Residual tumor (No vs. Yes)	<0.000	1.785	(1.512–2.107)	<0.000	1.776	(1.472–2.143)
Stage (Stage I vs. Stage II vs. Stage III vs. Stage IV)	<0.000	1.656	(1.345–2.038)	<0.000	1.484	(1.202–1.832)
Distant metastasis (age ≤60) (No vs. Yes)	0.001	3.481	(1.675–7.235)	0.653	1.086	(0.758–1.554)
Distant metastasis (age>60) (No vs. Yes)	0.296	1.217	(0.842–1.759)
Lymph node metastasis (age ≤60) (N0 vs. N1 vs. N2 vs. N3)	0.036	1.534	(1.029–2.287)	0.28	1.146	(0.895–1.467)
Lymph node metastasis (age>60) (N0 vs. N1 vs. N2 vs. N3)	0.001	1.475	(1.172–1.855)
Depth of invasion (age ≤60) (T1 vs. T2 vs. T3 vs. T4)	0.344	1.211	(0.815–1.799)	0.65	1.058	(0.829–1.351)
Depth of invasion (age>60)(T1 vs. T2 vs. T3 vs. T4)	<0.000	1.542	(0.214–1.960)
ERICH3-AS1 level (Low vs. High)	0.001	1.211	(1.080–1.358)	<0.000	1.256	(1.117–1.411)

Notes.