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. 2020 Jan 24;7:917. doi: 10.3389/fchem.2019.00917

Scheme 2.

Scheme 2

Synthetic pathways for compounds 79. Reagents and conditions: (i) ethyl cyanoacetate, 5 h; (ii) phenyl isothiocyanate, EtOH, 6 h; (iii) toluene sulfonyl chloride, benzene, pyridine (3 drops), 8 h.