Table 1.
Overall (N = 441,812) | NSCLC (n = 375,832) | SCLC (n = 65,980) | |
---|---|---|---|
Patient characteristics | |||
Sex, n (%) | |||
Male | 228,519 (51.7) | 196,454 (52.3) | 32,065 (48.6) |
Female | 213,293 (48.3) | 179,378 (47.7) | 33,915 (51.4) |
Age at diagnosis, n (%) | |||
<50 yr | 22,328 (5.1) | 19,224 (5.1) | 3,104 (4.7) |
50–54 yr | 33,619 (7.6) | 27,968 (7.4) | 5,651 (8.6) |
55–59 yr | 50,955 (11.5) | 42,054 (11.2) | 8,901 (13.5) |
60–64 yr | 62,839 (14.2) | 51,902 (13.8) | 10,937 (16.6) |
65–69 yr | 75,298 (17.0) | 62,838 (16.7) | 12,460 (18.9) |
70–74 yr | 71,798 (16.3) | 60,983 (16.2) | 10,815 (16.4) |
75–79 yr | 58,053 (13.1) | 50,616 (13.5) | 7,437 (11.3) |
≥80 yr | 66,922 (15.1) | 60,247 (16.0) | 6,675 (10.1) |
Racial or ethnic group, n (%) | |||
Non-Hispanic white | 349,842 (79.2) | 294,833 (78.4) | 55,009 (83.4) |
Non-Hispanic black | 48,060 (10.9) | 42,799 (11.4) | 5,261 (8.0) |
Non-Hispanic Asian | 9,483 (2.1) | 8,741 (2.3) | 742 (1.1) |
Hispanic | 12,081 (2.7) | 10,587 (2.8) | 1,494 (2.3) |
Other | 2,806 (0.6) | 2,441 (0.6) | 365 (0.6) |
Unknown | 19,540 (4.4) | 16,431 (4.4) | 3,109 (4.7) |
Health insurance status, n (%) | |||
Private | 117,168 (26.5) | 99,666 (26.5) | 17,502 (26.5) |
Medicare | 256,740 (58.1) | 219,916 (58.5) | 36,824 (55.8) |
Medicaid | 34,278 (7.8) | 28,118 (7.5) | 6,160 (9.3) |
Other government insurance | 7,023 (1.6) | 5,928 (1.6) | 1,095 (1.7) |
No insurance | 18,112 (4.1) | 15,009 (4.0) | 3,103 (4.7) |
Unknown | 8,491 (1.9) | 7,195 (1.9) | 1,296 (2.0) |
Charlson comorbidity score, n (%) | |||
0 | 24,687 (55.9) | 211,483 (56.3) | 35,404 (53.7) |
1 | 130,577 (29.6) | 110,304 (29.3) | 20,273 (30.7) |
≥2 | 64,348 (14.6) | 54,045 (14.4) | 10,303 (15.6) |
Health care provider characteristics | |||
Facility type, n (%) | |||
Academic | 140,344 (31.8) | 121,914 (32.4) | 18,430 (27.9) |
Nonacademic | 298,618 (67.6) | 251,260 (66.9) | 47,358 (71.8) |
Unknown | 2,850 (0.6) | 2,658 (0.7) | 192 (0.3) |
Hospital volume, median (IQR) | 524 (302–861) | 533 (304–871) | 500 (288–837) |
Tumor characteristics | |||
Histology*, n (%) | |||
Adenocarcinoma | 192,943 (43.7) | 192,943 (51.3) | — |
Squamous cell | 98,848 (22.4) | 98,848 (26.3) | — |
Other non–small cell | 84,041 (19.0) | 84,041 (22.4) | — |
Small cell | 65,980 (14.9) | — | 65,980 (100.0) |
Clinical stage at diagnosis, n (%) | |||
IA | 62,694 (14.2) | 61,123 (16.3) | 1,571 (2.4) |
IB | 26,984 (6.1) | 26,049 (6.9) | 935 (1.4) |
IIA | 17,456 (4.0) | 15,898 (4.2) | 1,558 (2.4) |
IIB | 15,199 (3.4) | 14,300 (3.8) | 899 (1.4) |
IIIA | 57,989 (13.1) | 48,881 (13.0) | 9,108 (13.8) |
IIIB | 34,088 (7.7) | 26,941 (7.2) | 7,147 (10.8) |
IV | 227,402 (51.5) | 182,640 (48.6) | 44,762 (67.8) |
Definition of abbreviations: IQR = interquartile range; NSCLC = non–small-cell lung cancer; SCLC = small-cell lung cancer.
NSCLC is subdivided into three distinct histology categories, whereas SCLC is considered a separate disease category.