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. Author manuscript; available in PMC: 2020 Feb 20.
Published in final edited form as: Phys Chem Chem Phys. 2019 Feb 20;21(8):4320–4330. doi: 10.1039/c8cp07293k

Fig. 2.

Fig. 2

Cooperativity in Na+ bindings. Panel (a) illustrates the giant component of the thrombin residues’ coupling network with respect to number of bound Na+. Panel (b) shows these coupling on the structure plot. The red and blue lines on both panels represent the positive and negative correlations respectively. A darker and thicker line indicates a stronger coupling.