Comparison 9. Sensitivity analyses.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Clinical Global Impressions scale improvement item (CGI‐I) : non‐response	13	1272	Risk Ratio (M‐H, Random, 95% CI)	0.66 [0.60, 0.74]
1.1 SSRIs	7	999	Risk Ratio (M‐H, Random, 95% CI)	0.65 [0.58, 0.74]
1.2 MAOIs	2	178	Risk Ratio (M‐H, Random, 95% CI)	0.80 [0.44, 1.44]
1.3 TCAs	1	40	Risk Ratio (M‐H, Random, 95% CI)	0.6 [0.38, 0.96]
1.4 Other medication	3	55	Risk Ratio (M‐H, Random, 95% CI)	0.59 [0.35, 0.98]
2 "Worst case" loss to follow up analysis	12	1275	Risk Ratio (M‐H, Random, 95% CI)	1.37 [1.12, 1.69]
2.1 SSRIs	7	1027	Risk Ratio (M‐H, Random, 95% CI)	1.52 [1.33, 1.74]
2.2 MAOIs	2	175	Risk Ratio (M‐H, Random, 95% CI)	0.28 [0.01, 5.42]
2.3 TCAs	1	43	Risk Ratio (M‐H, Random, 95% CI)	2.64 [0.86, 8.12]
2.4 Other medication	2	30	Risk Ratio (M‐H, Random, 95% CI)	1.12 [0.51, 2.47]
3 "Best case" loss to follow up analysis	12	1262	Risk Ratio (M‐H, Random, 95% CI)	1.52 [1.22, 1.90]
3.1 SSRIs	7	1018	Risk Ratio (M‐H, Random, 95% CI)	1.64 [1.44, 1.87]
3.2 MAOIs	2	172	Risk Ratio (M‐H, Random, 95% CI)	0.48 [0.06, 3.86]
3.3 TCAs	1	43	Risk Ratio (M‐H, Random, 95% CI)	3.5 [1.13, 10.81]
3.4 Other medication	2	29	Risk Ratio (M‐H, Random, 95% CI)	1.14 [0.52, 2.51]