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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Exp Neurol. 2019 Oct 25;323:113090. doi: 10.1016/j.expneurol.2019.113090

Figure 4. In vivo analysis of paclitaxel-induced neurotoxicity in zebrafish.

Figure 4.

This figure is in part re-used from (Lisse et al., 2016). (A) Tg(isl2b:GFP) zebrafish larva with fluorescent sensory neurons in the head and body, which innervate the epidermis. (B) Larval zebrafish treated with either DMSO control vehicle (top) or 22μM paclitaxel (bottom) after 1, 3, and 4 days following treatment begin. Sensory axons selectively degenerate in the distal tail fin of zebrafish around 3–4 days when treated with paclitaxel but not DMSO.