Table 4.

Characteristics of all studied breast cancer patients (N = 11 459) derived from the California Cancer Registry³⁴

	Stage at diagnosis
	Stage 0		Stage I		Stage II		Stage III		Stage IV		Missing
	No.	%	No.	%	No.	%	No.	%	No.	%	No.	%
Total	2335	100	3820	100	3443	100	1120	100	495	100	246	100
Age at diagnosis: mean (SD)	55.31 (11.93)		56.68 (12.97)		53.26 (13.2)		51.77 (12.74)		54.61 (13.62)		56.71 (15.91)
Year of breast cancer diagnosis
Before 2005	586	25.10	1106	28.95	1137	33.02	245	21.88	116	23.43	75	30.49
2005–2009	1039	44.50	1396	36.54	1277	37.09	474	42.32	189	38.18	118	47.97
2010–2015	710	30.41	1318	34.50	1029	29.89	401	35.80	190	38.38	53	21.54
Race
White	1762	75.46	3075	80.50	2699	78.39	871	77.77	394	79.60	191	77.64
Black	66	2.83	109	2.85	114	3.31	53	4.73	25	5.05	10	4.07
Asian/Pacific Islander	472	20.21	599	15.68	586	17.02	179	15.98	70	14.14	32	13.01
Other	21	0.90	23	0.60	17	0.49	5	0.45	2	0.40	11	4.47
Missing	14	0.60	14	0.37	27	0.78	12	1.07	4	0.81	2	0.81
Ethnicity
Hispanic	161	6.90	256	6.70	327	9.50	124	11.07	55	11.11	29	11.79
Non-Hispanic	2155	92.29	3553	93.01	3104	90.15	995	88.84	439	88.69	206	83.74
Missing	19	0.81	11	0.29	12	0.35	1	0.09	1	0.20	11	4.47
Neighborhood socioeconomic status (SES)a
Lowest quintile	104	4.45	158	4.14	151	4.39	62	5.54	40	8.08	25	10.16
Second quintile	188	8.05	298	7.80	313	9.09	122	10.89	64	12.93	29	11.79
Third quintile	315	13.49	489	12.80	520	15.10	188	16.79	81	16.36	35	14.23
Fourth quintile	468	20.04	735	19.24	666	19.34	230	20.54	105	21.21	46	18.70
Highest quintile	1202	51.48	2062	53.98	1737	50.45	496	44.29	195	39.39	106	43.09
Missing	58	2.48	78	2.04	56	1.63	22	1.96	10	2.02	5	2.03
Tumor receptor subtypeb
Estrogen (ER) and/or progesterone receptor (PR)-positive and HER2-negative	118	5.05	2336	61.15	1800	52.28	567	50.63	247	49.90	66	26.83
HER2-positive	48	2.06	545	14.27	651	18.91	254	22.68	117	23.64	22	8.94
Triple-negative	12	0.51	366	9.58	556	16.15	199	17.77	63	12.73	18	7.32
Missing	2157	92.38	573	15.00	436	12.66	100	8.93	68	13.74	140	56.91
Grade
1	209	8.95	1199	31.39	470	13.65	120	10.71	21	4.24	31	12.60
2	878	37.60	1551	40.60	1356	39.38	387	34.55	167	33.74	50	20.33
3	865	37.04	820	21.47	1420	41.24	521	46.52	177	35.76	64	26.02
Missing	383	16.40	250	6.54	197	5.72	92	8.21	130	26.26	101	41.06
Histology
Ductal	1989	85.18	3296	86.28	2919	84.78	923	82.41	413	83.43	168	68.29
Lobular	181	7.75	283	7.41	341	9.90	174	15.54	56	11.31	12	4.88
Other	165	7.07	241	6.31	183	5.32	23	2.05	26	5.25	66	26.83
Marital status
Single	333	14.26	577	15.10	512	14.87	184	16.43	95	19.19	41	16.67
Married	1577	67.54	2555	66.88	2322	67.44	747	66.70	289	58.38	122	49.59
Divorced	184	7.88	301	7.88	293	8.51	100	8.93	47	9.49	27	10.98
Widowed	169	7.24	286	7.49	217	6.30	55	4.91	44	8.89	24	9.76
Separated, unmarried, or Domestic partner	50	2.14	66	1.73	57	1.66	26	2.32	15	3.03	28	11.38
Missing	22	0.94	35	0.92	42	1.22	8	0.71	5	1.01	4	1.63
Payer
Not insured	11	0.47	17	0.45	22	0.64	6	0.54	3	0.61	5	2.03
Insurance, not otherwise specified	244	10.45	367	9.61	362	10.51	111	9.91	45	9.09	20	8.13
Managed care/HMO/PPO	1455	62.31	2218	58.06	2031	58.99	658	58.75	241	48.69	111	45.12
Medicaid	90	3.85	146	3.82	228	6.62	128	11.43	60	12.12	13	5.28
Medicare	424	18.16	900	23.56	639	18.56	162	14.46	118	23.84	61	24.80
Others	41	1.76	50	1.31	48	1.39	13	1.16	11	2.22	5	2.03
Missing	70	3.00	122	3.19	113	3.28	42	3.75	17	3.43	31	12.60

^aNeighborhood socioeconomic status (SES) quintile was assigned based on a previously developed measurement by Yost et al for cases diagnosed from 2000 to 2005, and Shariff-Marco et al for cases diagnosed 2006 to 2015.^30,31

^bTriple negative: estrogen receptor, progesterone receptor and HER2 all negative. HER2 positive: HER2 positive, regardless of estrogen receptor or progesterone receptor status.