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. 2020 Jan 21;130(2):1024–1035. doi: 10.1172/JCI131493

Figure 4. Expression of p-Akt and Angpt2 is increased in KO mice 1 day after pMCAO.

Figure 4

(A) Western blot analysis 1 day after pMCAO. (B) Densitometric analysis shows a significant increase of p-Akt in KO mice cortical protein lysates compared with WT mice. (C) Western blot analysis from ipsilateral hemisphere lysates 4 days after pMCAO. (D) There was no significant difference in p-Akt expression. (E) Angpt1, Angpt2; Western blot analysis. (F) One day after stroke, there is significantly elevated Angpt2 protein in KO mice lysates compared with WT mice. One-way ANOVA with Bonferroni’s post hoc test; n = 4–7 mice per group. *P < 0.05, **P < 0.01.