Fig. 4. Brain functional integration is a predictive marker for spreading effects of TMS.

(A) Individual classification between OCC- and FRO-TMS based on h values of a whole-brain parcellation yielded an overall prediction accuracy of 67%. (Left) Confusion matrix with the prediction accuracies for every class. (Middle) receiver operating characteristic (ROC) curve and discrimination probability [area under the curve (AUC) of 0.68]. (Right) Model (green line) significantly (P = 0.027, permutation testing) deviated from the null distribution (black dashed line) after permutation testing. (B) (Left) Spatial distribution of h across the entire cortex and (right) averaged across template networks.