Extended Data Table 2. Modelling of yeast SAGA subunits, domains and regions.
| Subunit / Chain ID | Domain | Residue range | Modelling method | Notes |
|---|---|---|---|---|
| Spt20 / B | 112-134 | de novo modelling | ||
| SEP | 135-224 | homology-modelling: 1SS6 | 153-168 missing | |
| 277-322 | de novo modelling | |||
| Wedge | 323-360 | de novo modelling | ||
| TIR | 389-416 | de novo modelling | ||
| TIR | 474-488 | de novo modelling | ||
| Spt3 / C | HF1 | 3-86 | homology-modelling: 6MZD | |
| 140-154 | de novo modelling | |||
| 191-209 | de novo modelling | |||
| HF2 | 210-312 | homology-modelling: 6MZD | 266-297 missing | |
| C-term | 313-337 | de novo modelling | ||
| Taf5 / D | LisH | 56-88 | de novo modelling | |
| 89-125 | homology-modelling: 6MZD | |||
| NTD | 149-281 | Crystal structure: 2J49 | ||
| 430-454 | de novo modelling | |||
| WD40 | 455-798 | homology-modelling: 6F3T & de novo modelling | 737-742 missing | |
| Taf6 / E | HF | 8-77 | homology-modelling: 6F3T | |
| 78-176 | de novo modelling | |||
| 188-220 | de novo modelling | |||
| HEAT | 221-467 | homology-modelling: 4ATG & de novo modelling | 235-242 missing 435-442 missing |
|
| Taf9 / F | HF | 30-101 | homology-modelling: 6F3T | 79-87 missing |
| C-term | 102-149 | de novo modelling | ||
| Taf10 / G | 67-86 | de novo modelling | ||
| HF | 87-196 | homology-modelling: 6MZD & de novo modelling | insertion 136-178 | |
| C-term | 197-206 | de novo modelling | ||
| Adal / H | N-term. | 181-267 | de novo modelling | |
| HF | 268-350 | homology-modelling: 6MZD | 327-331 missing | |
| 351-418 | de novo modelling | 388-393 missing | ||
| Taf12 / I | TIR | 353-413 | de novo modelling | |
| HF | 415-486 | homology-modelling: 6MZD | ||
| C-term | 487-525 | de novo modelling | ||
| Spt7 / K | 152-187 | de novo modelling | ||
| 728-754 | de novo modelling | |||
| 849-930 | de novo modelling | |||
| 952-974 | de novo modelling | |||
| HF | 975-1047 | homology-modelling: 6MZD | ||
| 1048-1085 | de novo modelling | |||
| Sfg73 / Q | anchor helices | 353-398 | de novo modelling | |
| 399-436 | de novo modelling | |||
| Tra1 / T | Finger | 1-950 | homology-modelling: 5OJS | 160-213, 259-278, 523-557, 652-672 missing |
| N-Clasp | 951-1142 | homology-modelling: 5OJS | ||
| Ring | 1143-2445 | homology-modelling: 5OJS | 2017-2021, 2044-2088, 2108-2114, 2131-2137, 2147-2153 missing | |
| C-Clasp | 2446-2598 | homology-modelling: 5OJS | ||
| FAT | 2599-3219 | homology-modelling: 5OJS | 2925-2935, 3183-3201 missing | |
| Kinase | 3220-3744 | homology-modelling: 5OJS | ||
| Chain U | poly-alanine | de novo modelling | Unassigned regions | |