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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Menopause. 2020 Feb;27(2):238–242. doi: 10.1097/GME.0000000000001438

Table 2.

Comparison of available treatment for UFs in menopause

Compound Advantages Disadvantages References
Tibolone Bone mineralization, reduces hot flushes, and may increase libido and vaginal lubrication Leucorrhea, weight gain (14)
Aromatase Inhibitor Used for treatment of breast cancer Hot flashes, bone loss, increased weight and gastralgia (15)
Selective estrogen receptor modulator Bone mineralization, benefit in lipid profile Tamoxifen can cause endometrial hyperplasia.
Depression, mood swings, dry skin, weight gain		 (16)
Uterine artery embolization Recovery is brief in 4 to 5 days, may return to normal activities in two weeks Postembolization syndrome: pain, fever and malaise (17)
Selective progesterone receptor modulator Decrease fibroid size, fast control of uterine bleeding Endometrial hyperplasia (18)