Table 1.
Probabilities of voxel-wise transitions from one ILD pattern to another by treatment assignment
| Whole Lung |
CYC Mean (SE) |
MMF Mean (SE) |
Total Mean (SE) |
||||||
| Baseline | NL | GG | LF | NL | GG | LF | NL | GG | LF |
| NL | 0.86 (0.02) |
0.10 (0.01) |
0.04 (0.01) |
0.88 (0.01) |
0.09 (0.01) |
0.03 (<0.01) |
0.87 (0.01) |
0.10 (0.01) |
0.03 (<0.01) |
| GG | 0.40 (0.17) |
0.50 (0.15) |
0.10 (0.13) |
0.37 (0.02) |
0.51 (0.02) |
0.12 (0.02) |
0.38 (0.02) |
0.50 (0.01) |
0.11 (0.01) |
| LF | 0.25 (0.02) |
0.15 (0.02) |
0.60 (0.03) |
0.22 (0.02) |
0.12 (0.01) |
0.66 (0.03) |
0.24 (0.01) |
0.14 (0.01) |
0.62 (0.02) |
| Most Severe Lobe | CYC Mean (SE) | MMF Mean (SE) | Total Mean (SE) | ||||||
| Baseline | NL | GG | LF | NL | GG | LF | NL | GG | LF |
| NL | 0.76 (0.03) |
0.15 (0.02) |
0.09 (0.02) |
0.75 (0.03) |
0.14 (0.01) |
0.11 (0.0) |
0.75 (0.02) |
0.15 (0.01) |
0.10 (0.01) |
| GG | 0.32 (0.03) |
0.52 (0.03) |
0.16 (0.03) |
0.28 (0.03) |
0.53 (0.02) |
0.19 (0.02) |
0.30 (0.20) |
0.53 (0.17) |
0.17 (0.02) |
| LF | 0.21 (0.03) |
0.16 (0.02) |
0.63 (0.04) |
0.18 (0.02) |
0.12 (0.02) |
0.70 (0.03) |
0.20 (0.02) |
0.14 (0.01) |
0.66 (0.02) |
NL= Normal Lung patterns; GG = Ground Glass patterns; LF = Lung Fibrosis patterns; CYC= Cyclophosphamide; MMF= Mycophenolate Mofetil; Mean and Standard Error (SE) of transitional probabilities (P Baseline→24 month pattern).