Table 1.
Baseline clinical characteristics of patients with MIBC treated with cystectomy and urinary diversion
| Characteristics | Total (N = 1340) | No preoperative chemotherapy (N = 821) | Preoperative chemotherapy (N = 519) | P value |
|---|---|---|---|---|
| Sex (N [%])a | ||||
| Male | 990 (73.9) | 600 (73.1) | 390 (75.1) | 0.40 |
| Female | 350 (26.1) | 221 (26.9) | 129 (24.9) | |
| Age (mean [SD])b | 70.84 (8.4) | 73.91 (7.7) | 65.97 (7.3) | < 0.001 |
| BMI (N [%])a | ||||
| < 18.5 | 28 (2.1) | 18 (2.2) | 10 (1.9) | 0.33 |
| 18.5–24.9 | 568 (42.4) | 361 (44.0) | 207 (39.9) | |
| 25–29.9 | 516 (38.5) | 312 (38.0) | 204 (39.3) | |
| ≥ 30 | 211 (15.8) | 118 (14.4) | 93 (17.9) | |
| Missing | 17 (1.3) | 12 (1.5) | 5 (1.0) | |
| Education (N [%])a | ||||
| Compulsory | 500 (37.3) | 336 (40.9) | 164 (31.6) | 0.003 |
| Upper secondary | 556 (41.5) | 320 (39.0) | 236 (45.5) | |
| University level | 275 (20.5) | 158 (19.2) | 117 (22.5) | |
| Missing | 9 (0.7) | 7 (0.8) | 2 (0.4) | |
| ASA-classification (N [%])a | ||||
| 1 | 161 (12.0) | 89 (10.8) | 72 (13.9) | 0.02 |
| 2 | 727 (54.2) | 431 (52.5) | 296 (57.0) | |
| 3 | 424 (31.6) | 280 (34.1) | 144 (27.8) | |
| 4 | 18 (1.3) | 15 (1.8) | 3 (0.6) | |
| Missing | 10 (0.8) | 6 (0.7) | 4 (0.8) | |
| Previous pelvic surgery or radiation (N [%])a | ||||
| No | 1109 (82.8) | 660 (80.4) | 449 (86.5) | 0.01 |
| Yes | 219 (16.3) | 154 (18.8) | 65 (12.5) | |
| Missing | 12 (0.9) | 7 (0.8) | 5 (1.0) | |
| Staging (N [%]) | ||||
| cT categorya | ||||
| T2 | 987 (73.7) | 627 (76.4) | 360 (69.4) | 0.03 |
| T3 | 249 (18.6) | 139 (16.9) | 110 (21.2) | |
| T4a | 87 (6.5) | 45 (5.5) | 42 (8.1) | |
| T4b | 17 (1.3) | 10 (1.2) | 7 (1.4) | |
| cN categorya | ||||
| N0 | 1122 (83.7) | 714 (87.0) | 408 (78.6) | <0.001 |
| N + (incl.N1-3, N +) | 146 (10.9) | 61 (7.4) | 85 (16.4) | |
| Missing (incl.Nx) | 72 (5.4) | 46 (5.6) | 26 (5.0) | |
| Hospital volume (no. of operations/year)a | ||||
| ≤ 20 | 404 (30.2) | 275 (33.5) | 129 (24.9) | <0.001 |
| 20–50 | 428 (31.9) | 220 (26.8) | 208 (40.1) | |
| > 50 | 507 (37.8) | 326 (39.7) | 181 (34.9) | |
| Missing | 1 (0.1) | 0 (0.0) | 1 (0.2) | |
aChi square test or Fisher’s exact test
bT test