Table 3.
Risk for complications, reoperations and death within 90 days from cystectomy comparing patients with and without preoperative chemotherapy treatment
| Outcomes | Total (N = 1340) | No preoperative chemotherapy (N = 821) | Preoperative chemotherapy (N = 519) | ||
|---|---|---|---|---|---|
| N (%) | N (%) | OR (95%C) | N (%) | OR (95%CI)b | |
| Any complication | 636 (47.5) | 382 (46.5) | Ref | 254 (48.9) | 1.06 (0.82–1.39) |
| Highest Clavien–Dindoa | |||||
| I–II | 291 (21.7) | 165 (20.1) | Ref | 126 (24.3) | 1.18 (0.84–1.65)c |
| III | 238 (17.8) | 140 (17.1) | Ref | 98 (18.9) | 1.12 (0.78–1.61)c |
| IV | 39 (2.9) | 26 (3.2) | Ref | 13 (2.5) | 0.70 (0.31–1.57)c |
| V | 25 (1.9) | 21 (2.6) | Ref | 4 (0.8) | 0.59 (0.14–2.40)c |
| Gastrointestinal complication | 128 (9.6) | 94 (11.4) | Ref | 34 (6.6) | 0.49 (0.30–0.81) |
| Cardiovascular complication | 74 (5.5) | 47 (5.7) | Ref | 27 (5.2) | 0.96 (0.53–1.74) |
| Infectious complication | 338 (25.2) | 197 (24.0) | Ref | 141 (27.2) | 1.07 (0.79–1.45) |
| Abdominal wall/stoma complication | 153 (11.4) | 93 (11.3) | Ref | 60 (11.6) | 1.03 (0.68–1.57) |
| Urinary tract complication | 102 (7.6) | 61 (7.4) | Ref | 41 (7.9) | 1.15 (0.70–1.89) |
| Nerve damage | 7 (0.5) | 5 (0.6) | Ref | 2 (0.4) | 0.26 (0.05–1.51) |
| Unscheduled readmission | 347 (25.9) | 208 (25.3) | Ref | 139 (26.8) | 1.21 (0.89–1.64) |
| Reoperation | 173 (12.9) | 106 (12.9) | Ref | 67 (12.9) | 1.02 (0.68–1.51) |
| Death | 66 (4.9) | 52 (6.3) | Ref | 14 (2.7) | 0.75 (0.36–1.55) |
aNumbers do not add to total due to missing data
bModel with propensity score
cRelative risk ratio was estimated using multinomial logistic regression using patients without complication as the comparison group