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. 2020 Jan 31;6:3. doi: 10.1038/s41523-020-0145-3

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Primary TNBC cancer samples from the Discovery cohort (N = 110) (not given chemotherapy) were evaluated to identify DNA methylation markers high in recurring and low in nonrecurring cancers. Candidate markers were then tested in the IBCSG No Chemo Test cohort (not given chemotherapy) (N = 49). Also evaluated was the combined IBCSG and Institutional Chemo cohort (N = 120) obtained from patients who received chemotherapy. Cases that recurred after 5 years and controls with less than 5 years of follow-up were excluded (5-year censoring).