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Mean values of scoring index (SI) for erythema, itch, scaling and irritation on face and chest at baseline (W0), after 7 (W1) and 14 (W2) days of treatment (a, c). Mean values of visual analog scale (VAS, range 0–10) for itch, erythema, scaling, irritation, pain and hot sensation at W0, W1 and W2 (b, d). Statistical analyses were performed by Wilcoxon matched pairs test (*p < 0.05; **p < 0.01, ***p < 0.001)
