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. 2020 Jan 3;10(1):191–202. doi: 10.1007/s13555-019-00349-8

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 3 — Effect of 3-in-1 NFS on procollagen type I expression in UV-exposed skin explants. a Mean area of the dermis positive for procollagen type I expression. Error bars correspond to the mean area (± SEM) of 64 images. Significance levels are calculated versus untreated UV-exposed skin (UV). **p < 0.01. NIC non-irradiated control, UV UV-exposed untreated skin. b Representative images showing fluorescence staining of procollagen type I (red) in skin dermis from non-irradiated skin (left), UV-exposed skin (center), and 3-in-1 NFS-treated (right) skin. All images were taken at ×10 magnification