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. 2020 Jan 31;10:1587. doi: 10.1038/s41598-020-58350-7

Table 1.

Latent Class Analysis estimates true prevalence of FFV to be 94.8%.

Model qPCR ELISA Prevalence (%) DIC ΔDIC w
Se (%) Sp (%) Se (%) Sp (%)
UIP & Cov 66.1 ± 4.2 42.3 ± 21.4 65.4 ± 4.3 45.9 ± 21.8 94.8 ± 5 241.2 0 1.0
IP & Cov 74.2 ± 3.3 94.6 ± 3.5 80.2 ± 5.1 95.0 ± 3.2 85.0 ± 4.5 261.2 20 0.0
UIP 83.0 ± 8.5 87.5 ± 8.4 95.3 ± 3.3 67.9 ± 16.5 69.0 ± 8.8 272.9 31.7 0.0
IP 74.5 ± 3.4 96.5 ± 2.7 94.3 ± 2.2 96.3 ± 3 77.6 ± 3.8 282.2 41 0.0
Model Average 66.1 ± 4.2 42.3 ± 21.4 65.4 ± 4.3 45.9 ± 21.8 94.8 ± 5

Average model coefficients ± standard deviation for the sensitivity (Se) and specificity (Sp) of qPCR and ELISA as well as true prevalence of FFV based on Bayesian Latent Class Analysis. Deviance Information Criterion (DIC) values and model weights (w) suggest uninformative priors and covariance between qPCR and ELISA to be the most parsimonious model. UIP = uninformative priors; IP = informative priors; Cov = covariance.