Table 1.
Clinicopathological data and immunostaining intensity of PTHR1 and PTHrP for those cases collected from ASAP laboratory with survival time (ASAP-50).
| # | Breed | Sex | Age | Body part | Tumour grade | Survival time (days) | PTHR1 immuno-staining intensity | PTHrP immune-staining intensity |
|---|---|---|---|---|---|---|---|---|
| 1 | Staffordshire Bull Terrier | F | 12 | Humerus | 1 | 28* | Low | Low |
| 2 | Greyhound | M | 10 | Tibia | 1 | 90 | High | High |
| 3 | Rottweiler | M | 1 | Humerus | 1 | 114 | High | Low |
| 4 | Boxer Cross | M | 11 | Femur | 1 | 458 | Low | Low |
| 5 | Mastiff | F | 7 | Rib | 1 | 14* | Low | Low |
| 6 | Bulldog | M | 10 | Tibia | 1 | 193 | Low | Low |
| 7 | Labrador Retriever | M | 8 | Radius | 1 | 702 | Low | Low |
| 8 | Giant Schnauzer | M | 7 | Radius | 2 | 380 | High | High |
| 9 | Boxer | F | 10 | Rib | 2 | 240* | Low | Low |
| 10 | German Shepherd Dog | F | 11 | Radius | 2 | 485 | High | High |
| 11 | Rottweiler Cross | F | 8 | Jaw | 1 | 83* | High | High |
| 12 | Spoodle | M | 10 | Rib | 2 | 71* | High | Low |
| 13 | Schnauzer Cross | M | 11 | Rib | 2 | 4* | Low | Low |
| 14 | Doberman | F | 10 | Tibia | 1 | 240 | High | Low |
| 15 | Rottweiler | M | 8 | Humerus | 1 | 150* | High | Low |
| 16 | Rottweiler | F | 9 | Jaw | 1 | 157* | High | Low |
| 17 | Golden Retriever | M | 8 | Humerus | 1 | 65* | Low | Low |
| 18 | Golden Retriever | M | 14 | Femur | 2 | 115* | High | High |
| 19 | Rottweiler Cross | M | 9 | Ilium | 1 | 1* | High | Low |
| 20 | Doberman | M | 9 | Radius | 1 | 104* | Low | Low |
| 21 | Labrador | F | 7 | Radius | 2 | 277 | Low | Low |
| 22 | Jack Russell Terrier | M | 8 | Jaw | 2 | 21* | High | Low |
| 23 | Rottweiler | F | 4 | Humerus | 2 | 96 | High | Low |
| 24 | Blue Heeler | M | 12 | Tibia | 1 | 150* | High | High |
| 25 | Golden Retriever | M | 13 | Jaw | 1 | 180* | Low | High |
| 26 | Mastiff Cross | M | 6 | Femur | 2 | 470 | Low | Low |
| 27 | Cairn Terrier | F | 12 | Humerus | 1 | 155 | High | High |
| 28 | Boxer Cross | F | 15 | Jaw | 1 | 43* | High | High |
| 29 | Jack Russell Terrier | F | 9 | Scapula | 2 | 27* | High | High |
| 30 | Labrador | M | 11 | Humerus | 1 | 578 | High | High |
| 31 | Cavalier Cross | M | 10 | Humerus | 2 | 26 | High | High |
| 32 | Labrador | M | 13 | Jaw | 2 | 21* | High | High |
| 33 | Border Collie | M | 6 | Femur | 2 | 17* | High | Low |
| 34 | Labradoodle | M | 3 | Rib | 2 | 11* | High | High |
| 35 | Pointer Cross | F | 9 | Radius | 1 | 17* | High | Low |
| 36 | Rottweiler Cross | F | 9 | Humerus | 2 | 270 | High | Low |
| 37 | Border Collie Cross | F | 13 | Scapula | 2 | 135* | Low | Low |
| 38 | American Staffordshire Bull Terrier | M | 12 | Vertebrae | 1 | 54* | High | Low |
| 39 | White Swiss Shepherd Dog | F | 9 | Ilium | 2 | 3* | High | High |
| 40 | Maltese Cross | M | 13 | Jaw | 2 | 47* | High | High |
| 41 | SBT Cross | F | 9 | Humerus | 2 | 76 | High | High |
| 42 | Alaskan Malamute | M | 6 | Radius | 1 | 82 | High | Low |
| 43 | Rottweiler | F | 11 | Tibia | 2 | 288 | High | High |
| 44 | Curly Coated Retriever | F | 11 | Humerus | 1 | 90 | High | High |
| 45 | Boxer | F | 7 | Skull | 1 | 24* | High | High |
| 46 | Labrador | M | 8 | Humerus | 2 | 14* | High | High |
| 47 | Jack Russell Terrier | M | 14 | Jaw | 2 | 154* | High | High |
| 48 | Labrador | M | 7 | Femur | 1 | 7* | High | High |
| 49 | Greyhound | M | 11 | Femur | 1 | 655 | Low | High |
| 50 | Labradoodle | M | 7 | Humerus | 1 | 142* | High | High |
*Cases excluded from the larger ASAP-50 group of dogs with OS to make a homogenous group (ASAP-20). Excluded dogs had no surgical or no chemotherapy, or had pulmonary metastasis at presentation, or presented with OS localised in axial parts, or still alive at the date of data collection, or died because of post-surgical complications; SBT, Staffordshire Bull Terrier; F, female; M, male.