Table 2.

Multivariate regression final models with memory function test and diabetes in ELSA-Brasil (baseline 2008–2010) n = 14,444. Note. Total Col-HDL-C-Total cholesterol/High density cholesterol ratio. β[CI95%] – coefficient β and 95% confidence interval; R²-R² adjusted. Model 1- Adjustment by age, sex and education, Model 2 - Model 1 plus hypertension, coronary disease and depression. Model 3 - Model 2 plus physical activity, smoking, alcohol use, total cholesterol / HDL-C. *p < 0.05; **p < 0.01; ***p < 0.001 Final models included variables with p < 0.05.

Variable	Memory test (learning, recall and word recognition test)
	Model 1 β[CI 95%] R20.21	Model 2 β[CI 95%] R20.21	Model 3 β[CI 95%] R20.22	Final Model β[CI 95%] R20.21
Diabetes	−0.58 [−0.82, −0.34]***	−0.58 [−0.82, − 0.34]***	−0.57 [−0.82, − 0.31]***	−0.53 [−0.77, − 0.29]***
Age (years)
35 a 44	1	1	1	1
45 a 54	−0.75 [−0.98, −0.51]***	−0.75 [−0.98, −0.51]***	−0.60 [−0.84, −0.35]***	−0.64 [−0.87, −0.40]***
55 a 64	−1.78 [−2.03, −1.52]***	−1.78 [−2,03–1.52]***	−1.68 [−1.96, −1.41]***	−1.68 [−1.94, −1.42]***
65 a 74	−3.70 [−4.04, −3.36]***	−3.70 [−4.02, −3.36]***	−3.63 [−3.99, −3.26]***	−3.65 [−3.99, −3.31]***
Female sex	2.07 [1.90,2.25]***	2.07 [1.90, 2.25]***	2.08 [1.87, 2.28]***	2.00 [1.81, 2.20]***
Education
Incomplete fundamental	1	1	1	1
Complete fundamental	2.23[1.71,2.75]***	2.23[1.71,2.75]***	2.27[1.75,2.80]***	2.20[1.68,2.71]***
High schoool	4.30[3.88,4.72]***	4.30[3.88,4.72]***	4.22[3.79,4.66]***	4.22[3.80,4.65]***
University degree	7.21[6.80,7.63]***	7.22[6.80,7.63]***	7.09[6.66,7.52]***	7.06[6.65,7.47]***
Smoking
No			1	1
Former			−0.46 [−0.67, −0.25]***	−0.45 [−0.65, −0.24]***
Current			−0.90 [−1.19, −0.62]***	−0.88 [−1.16, −0.61]***
Alcoho l (g/week)
1–175			1	1
176–350			0.68[0.31, 1.06]***	0.66[0.29, 1.03]**
>350			0.61[−0.03, 1.19] *	0.42[−0.15, 0.98]
Total Col-HDL-C			−0.13[−0.22, −0.04]**	−0.15 [−0.24, −0.06]***