Table 3.

Final models of multivariate regression with phonemic verbal fluency test (letter F) and diabetes in ELSA-Brasil (baseline 2008–2010) n = 14,444. Note. β[CI95%] – coefficient β and 95% confidence interval; R²-R² adjusted. Model 1- Adjustment by age, sex and education. Model 2 - Model 1 plus hypertension, coronary disease and depression. Model 3 - Model 2 plus physical activity, smoking, alcohol use, total cholesterol/HDL-C. *p < 0.05; **p < 0.01; ***p < 0.001 Final models included variables with p < 0.05.

Variable	Phonemic verbal fluency (letter F)
	Model 1 β[CI 95%] R20.17	Model 2 β[CI 95%] R20.18	Model 3 β[CI 95%] R20.18	Final Model β[CI 95%] R20.18
Diabetes	−0.57[−0.75, −0.38]***	−0.52[−0.71, −0.33]***	−0.53[−0.72, −0.33]***	−0.50[−0.69, −0.31]***
Age (years)
35 a 44	1	1	1	1
45 a 54	−0.33[−0.51, −0.15]***	−0.30[−0.49, −0.12]***	−0.38[−0.57, −0.20]***	−0.37[−0.56, −0.19]***
55 a 64	−0.81[−1.00, −0.61]***	−0.71[−0.91, −0.50]***	−0.83[−1,04–0.63]***	−0.85[−1.05, −0.65]***
65 a 74	−1.36[−1.62, −1.10]***	−1.26[−1.53, −0.99]***	−1.38[−1.66, −1.11]***	−1.37[−1.63, −1.10]***
Female sex	0.13 [−0.01,0.27]	0.11 [−0.03, 0.25]	0.18 [0.03, 0.33]*	0.14 [0.01, 0.28]*
Education
Incomplete fundamental	1	1	1	1
Complete fundamental	1.58[1.20,1.96]***	1.52[1.13,1.90]***	1.50[1.11,1.89]***	1.57[1.19,1.95]***
High school	3.57[3.26,3.88]***	3.56[3.25,3.87]***	3.52[3.21,3.84]***	3.54[3.23,3.85]***
University degree	5.83[5.53,6.13]***	5.80[5.49,6.10]***	5.76[5.45,6.07]***	5.77[5.46,6.07]***
Hipertension
No		1	1	1
Yes		−0.35[−0.50, −0.20]***	−0.34[−0.50, −0.19]***	−0.33[−0.48, −0.18]***
Depression
No		1	1	1
Yes		0.66[0.36,0.96]***	0.66[0.35,0.96]***	0.66[0.37,0.96]***
Smoking
No			1	1
Former			0.39[0.23,0.55]**	0.40[0.25,0.56]**
Current			0.14[−0.08,0.36]	0.14[−0.07,0.35]
Physical activity
Low			1	1
Moderate			0.25[0.06,0.44]**	0.27[0.09,0.46]**
High			0.21[−0.07,0.48]	0.17[−0.10,0.44]