Table 3.
Haplotypes of ten probands with the BRCA1 c.815_824dup10 mutation and 15 healthy controls.
Patient | D17S1793 | D17S1320 | D17S855 | D17S1323 | D17S1325 | D17S951 | D17S1183 | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Index cases | AB1 | 193 | 195 | 186 | 188 | 144 | 146 | 156 | 156 | 171 | 173 | 170 | 178 | 129 | 146 |
AT | 193 | 195 | 188 | 190 | 144 | 144 | 156 | 158 | 157 | 173 | 172 | 174 | 135 | 146 | |
FDF | 193 | 193 | 195 | 195 | 144 | 152 | 150 | 156 | 173 | 175 | 168 | 172 | 120 | 120 | |
FW | 193 | 195 | 186 | 186 | 144 | 152 | 154 | 156 | 171 | 173 | 170 | 172 | 146 | 150 | |
FY1 | 193 | 193 | 224 | 224 | 144 | 152 | 156 | 158 | 173 | 175 | 172 | 174 | 129 | 148 | |
ML1 | 193 | 193 | 213 | 224 | 144 | 148 | 150 | 156 | 173 | 173 | 172 | 172 | 124 | 139 | |
NA | 195 | 195 | 195 | 195 | 144 | 150 | 154 | 156 | 175 | 179 | 170 | 178 | 124 | 124 | |
SM | 193 | 193 | 190 | 190 | 144 | 144 | 156 | 162 | 169 | 173 | 168 | 170 | 124 | 146 | |
SN | 193 | 193 | 192 | 192 | 144 | 148 | 156 | 156 | 173 | 175 | 174 | 176 | 124 | 124 | |
WM | 193 | 197 | 203 | 224 | 140 | 144 | 156 | 158 | 167 | 171 | 170 | 172 | 120 | 129 | |
Healthy controls | T33 | 192 | 200 | 193 | 196 | 152 | 152 | 150 | 154 | 171 | 177 | 168 | 172 | 121 | 121 |
T37 | 193 | 195 | 187 | 193 | 152 | 152 | 152 | 154 | 169 | 169 | 170 | 174 | 121 | 121 | |
T38 | 192 | 193 | 191 | 193 | 152 | 155 | 152 | 154 | 171 | 173 | 168 | 172 | 121 | 129 | |
T141 | 192 | 195 | 185 | 189 | 144 | 154 | 156 | 159 | 157 | 171 | 170 | 174 | 121 | 121 | |
T142 | 193 | 195 | 203 | 205 | 150 | 159 | 152 | 154 | 175 | 175 | 174 | 176 | 121 | 124 | |
T49 | 193 | 193 | 187 | 191 | 147 | 154 | 152 | 156 | 157 | 175 | 170 | 174 | 121 | 121 | |
T52 | 193 | 193 | 187 | 189 | 144 | 149 | 154 | 154 | 175 | 175 | 174 | 176 | 121 | 124 | |
T53 | 189 | 193 | 189 | 191 | 144 | 150 | 154 | 154 | 167 | 175 | 174 | 174 | 121 | 121 | |
T55 | 191 | 193 | 188 | 191 | 152 | 152 | 154 | 159 | 157 | 173 | 176 | 176 | 121 | 128 | |
T56 | 193 | 193 | 188 | 193 | 144 | 152 | 154 | 156 | 168 | 171 | 168 | 174 | 121 | 121 | |
T61 | 193 | 193 | 189 | 193 | 148 | 152 | 154 | 152 | 171 | 171 | 170 | 176 | 121 | 124 | |
T63 | 193 | 193 | 185 | 193 | 150 | 152 | 154 | 159 | 171 | 175 | 170 | 180 | 121 | 124 | |
T67 | 191 | 193 | 191 | 203 | 150 | 152 | 150 | 152 | 171 | 175 | 168 | 172 | 121 | 124 | |
T70 | 189 | 197 | 185 | 191 | 150 | 152 | 152 | 154 | 167 | 169 | 174 | 174 | 121 | 121 | |
T83 | 193 | 195 | 189 | 191 | 152 | 154 | 154 | 154 | 157 | 171 | 168 | 170 | 121 | 129 |
Bold are genotypes of the haplotype segregating with BRCA1 c.815_824dup10 mutation.