Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mutational analyses of the interaction between PTPδ D2 and Liprin-α3 tSAM by SPR experiments.
| Mutation | KD (µM) |
|---|---|
| Liprin-α3 tSAM | |
| WT | 10.7 ± 3.3 |
| ΔN9 | 17.4 ± 0.15 |
| L808A | 19.7 ± 0.58 |
| R816A | 29.8 ± 1.3 |
| W856A | ND |
| E976A | >40 |
| L978A | ND |
| PTPδ D2 | |
| F1503A | 8.3 ± 2.8 |
| D1504A | 18.0 ± 3.8 |
| Y1506A | 11.4 ± 2.3 |
| Y1373A | ND |
| L1380A | >40 |
| F1399A | 32.0 ± 6.1 |
| R1397A | ND |
| F1430A | ND |
Source data are provided as a Source Data file.
WT wild type, ND not detectable.
