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. 2020 Jan 31;5:10. doi: 10.1038/s41541-020-0160-2

Fig. 2. IgG and IgM antibody titers against MSP1-D after immunization with SumayaVac-1.

Fig. 2

Blood samples were collected from the vaccines on the days indicated and the a IgG-specific and b IgM-specific MSP1-D antibody titers were determined by ELISA. The data points represent the geometric means ± 95% confidence interval of each cohort. Crossed circles indicate samples from single individuals. Red arrows indicate the days of immunization. Dashed lines indicate reference titers obtained from pooled sera from semi-immune individuals from Nouna, Burkina Faso (orange line, n = 11)48 and from Kisumu, Kenya (black line, NIBSC code 10/198).104 Controls comprise the placebo and the GLA-SE vaccinees. The pie chart shows the average percentile distribution of IgG subclasses after three immunizations with SumayaVac-1 (day 85, n = 24).