Table 1.
Demographics and cellular doubling time (mean +− standard deviation).
| IPD | Controls | P-value | |
|---|---|---|---|
| Age (mean +− SD) [years] | 66.3 ± 7.3 | 66.1 ± 5 | 0.901 |
| Gender M/F | 25/16 | 4/17 | 0.001 |
| PD duration | 6.6 ± 5.2 | NA | NA |
| UPDRS motor score | 10.4 ± 5 | 0.6 ± 1 | <0.001 |
| Levodopa dosage | 589.8 ± 348.9 | NA | NA |
| MMSE score | 27.9 ± 4.7 | 29.1 ± 1.3 | 0.172 |
| FAB score | 15.4 ± 2.5 | 16 ± 2.6 | 0.197 |
| UPSIT score | 19.5 ± 7.1 | 31 ± 4.7 | <0.001 |
| NMS score | 8.1 ± 5.3 | 2.7 ± 2.5 | <0.001 |
| Doubling time [days] | 16.1 ± 18.5 | 4.9 ± 4.2 | <0.001 |
Abbreviations: UPDRS = Unified Parkinson’s Disease Rating Scale; MMSE = MiniMental State Examination; FAB = Frontal Assessment Battery; UPSIT = University of Pennsylvania Smell Identification Test; NMS = Non-motor symptom score.