Supplementary Figure 1.

IKBKE inhibitor Amlexanox reduced cell viability, cell motility, invasion and cancer stem cell sphere formation of PDAC cells. A, Five PDAC cell lines were treated with increasing concentrations of amlexanox and MTT assay was performed after 72 hours. B, Amlexanox significantly inhibited L3.6pl cell sphere formation compared to vehicle. C and D, L3.6pl cells were plated with indicated amounts of Amlexanox 0or vehicle for cell invasion (C) or migration (D) assays. *P < .05 and **P < .002.