Figure 5.

FGF13 is not abundant in adipose tissues, and adipose-specific Fgf13 heterozygous (Het) knockout does not recapitulate weight gain. A) Western blot demonstrating FGF13 expression in various tissues. This is a representative image of 3 successful experiments. B) Growth chart of Adipoq-Cre⁺;Fgf13^+/fl mice and Adipoq-Cre⁺ littermate controls housed at 30°C; n = 5–6/genotype. GAPDH, glyceraldehyde 3-phosphate dehydrogenase. Two-way repeated measures ANOVA was used to assess main effects of genotype and time, as well as interaction effects. Comparisons between genotypes at each time point were made using Tukey’s test for multiple comparisons.